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Kimon C Kanelakis Selected Research

Hypoxia (Hypoxemia)

6/2011Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.
12/2010Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues.
7/2009Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases.

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Kimon C Kanelakis Research Topics

Disease

3Hypoxia (Hypoxemia)
06/2011 - 07/2009
2Inflammation (Inflammations)
08/2015 - 06/2011
1Iron Deficiencies
08/2015
1Anemia
06/2011
1Metabolic Diseases (Metabolic Disease)
06/2011
1Ulcerative Colitis
06/2011

Drug/Important Bio-Agent (IBA)

3EnzymesIBA
08/2015 - 12/2010
2Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
08/2015 - 06/2011
1JNJ-42905343IBA
08/2015
1Peptidoglycan (Murein)IBA
08/2015
1Polysaccharides (Glycans)IBA
08/2015
1Prolyl-Hydroxylase InhibitorsIBA
06/2011
11- (5- chloro- 6- (trifluoromethoxy)- 1H- benzoimidazol- 2- yl)- 1H- pyrazole- 4- carboxylic acidIBA
06/2011
1Erythropoietin Receptors (Erythropoietin Receptor)IBA
06/2011
1ErythropoietinFDA Link
06/2011
1Hypoxia-Inducible Factor 1IBA
12/2010
1Proline (L-Proline)FDA Link
07/2009
1Proteins (Proteins, Gene)FDA Link
07/2009
1Transcription Factors (Transcription Factor)IBA
07/2009